Highlights from Sepsis surviving Campaign 2016:Â Base on ProCESS, ProMISe and ARISE trials, Â all 3 trials confirmed that there was no survival benefit of EGDT compared to usual resuscitation. Â However, in all three studies patients had early antibiotics, >30ml/kg of IVF prior to randomization. Â We need therefore to keep in mind that the practice has changed. Source control: empiric broad-spectrum therapy Abx to cover all likely pathogens within 1hr Initial resuscitation: 30ml/kg of IV crystalloid fluid in first 3 hours … Continue reading “Pressors”