{"id":921,"date":"2013-10-10T14:57:34","date_gmt":"2013-10-10T14:57:34","guid":{"rendered":"http:\/\/jacobimed.org\/NS\/?page_id=921"},"modified":"2015-01-18T02:31:56","modified_gmt":"2015-01-18T02:31:56","slug":"cardiology-clinical-questions","status":"publish","type":"page","link":"https:\/\/jacobimed.org\/old\/ambulatory\/mlove\/practical-practice\/chest-pain\/chest-pain-homepage\/cardiology-clinical-questions\/","title":{"rendered":"Cardiology Clinical Questions"},"content":{"rendered":"<h1 class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\">Management of Chronic Disease\/ Cardiology for the Internist<\/span><\/h1>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\">\u00a0<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Garamond','serif'; font-size: 14pt;\"><em>Here are a few common clinical scenarios.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>Your job now is to say what you would do in these situations and <strong>why<\/strong>.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>In extreme detail.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>Detail the parts of your recommendation which stand on a firm evidence base and the parts which stand on shaky or non-existent evidence.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>The idea is to practice making clinical decisions<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>in a hyper-rational, evidence based way.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>This entails knowing the evidence-base, extrapoloating from the evidence base where appropriate, and winging it well when there is no good evidence. Secondary sources such as the In the Clinic article attached here, UptoDate, The Hopkins module, and The Cochrane reviews are good places to start your research.\u00a0 However, your presentation should refer to important primary studies and not just quote recommendations or guidelines.\u00a0 <\/em><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\">\u00a0<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\">Patient 1:<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>A 65 year old woman with type II diabetes, hypertension, and hypercholesterolemia complains of<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>shortness of breath when climbing hills.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>Her meds include aspirin, zocor, lisinopril, hctz, metformin, and glyburide.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>Exam is normal including BP of 120\/ 79 and HR 72.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>Resting EKG shows nonspecific T wave changes similar to baseline.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>On a treadmill stress test, she reaches 100% of MPHR.<span style=\"mso-spacerun: yes;\">\u00a0\u00a0 <\/span>There are half mm horizontal ST depressions in II, III, and aVF at stage III that correspond to shortness of breath.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>The thallium portion of the test shows a small perfusion defect in the inferior wall of moderate intensity.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\">\u00a0<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\"><span style=\"mso-tab-count: 1;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>&#8211; Should the patient receive a cardiac catheterization?<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\"><span style=\"mso-tab-count: 1;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>&#8211; What if she is started on beta blockers and becomes asymptomatic?<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>Is catheterization indicated?<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\"><span style=\"mso-tab-count: 1;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>-What if she cannot tolerate beta blockers or nitrates and remains symptomatic only when climbing hills?<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\"><span style=\"mso-tab-count: 1;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>&#8211; Which therapies, medical or interventional, alter the prognosis of CAD, and by how much?<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\">\u00a0<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\">Patient 2:<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>A 72 year-old woman with a history of diabetes, hypertension and coronary artery disease diagnosed by catheterization 6 months ago (70%<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>OM1 lesion, a 40% RCA, and a 30% LAD, normal EF and wall motion) comes to walk-in complaining of right parasternal sticking chest pain similar to the pain which led to her catheterization. since this morning<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>The pain had gone away when she took her daily dose of isosorbide mononitrate but started again two hours ago while she was mopping.<span style=\"mso-spacerun: yes;\">\u00a0 This time it<\/span>\u00a0lasted about ten minutes, went away, and then came back while she was watching television and lasted another ten minutes.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>She had palpitations and slight shortness of breath with the first bout but not with the second.<span style=\"mso-spacerun: yes;\">\u00a0\u00a0 <\/span>Exam is normal and EKG is unchanged.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\"><span style=\"mso-tab-count: 1;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>&#8211; What is the probability that she is suffering an MI?<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>Should she be admitted?<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\"><span style=\"mso-tab-count: 1;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>&#8211; What if the chest wall was tender?<span style=\"mso-spacerun: yes;\">\u00a0\u00a0 <\/span>Would the probability change?<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\"><span style=\"mso-tab-count: 1;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>&#8211; What if the pain was left sided?<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>What if it was squeezing?<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\"><span style=\"mso-tab-count: 1;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>&#8211; What if the catheterization had been two years ago and she had come to the hospital five times since with a similar presentation?<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\">\u00a0<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\">Patient 3:<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>A 54 year old woman without known past medical history (she hasn\u2019t been to a doctor in twenty years) except 30 years of cigarette smoking presents with 6 months of progressive DOE, orthopnea, and edema.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>There is no history of chest pain.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span>Exam is notable for BP of 170\/90, HR 92, bibasilar rales, S3 gallop, and 2+ dependent edema.<span style=\"mso-spacerun: yes;\">\u00a0\u00a0 <\/span>Workup reveals normal labs except for Cr 1.9, UA trace protein, LDL 130, HDL 42, CMG with PVC on CXR, LBBB on EKG, and echo with EF 40%, global hypokinesis, and LVH.<span style=\"mso-spacerun: yes;\">\u00a0 <\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\"><span style=\"mso-tab-count: 1;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>&#8211; What further workup, if any, is warranted?<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt;\"><span style=\"line-height: 115%; font-family: 'Times New Roman','serif'; font-size: 12pt;\"><span style=\"mso-tab-count: 1;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>&#8211; With which medicines should she be treated, started in which order?<span style=\"mso-spacerun: yes;\">\u00a0<\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt; font-size: 14px;\">Patient 4: \u00a0You have taken a new job at the Avoid Evidence Clinic of Medicine replacing Dr. Methusalah, who recently died. \u00a0Your first patient is Mrs. Faithful, a 74 yo woman with a history of atrial fibrillation. \u00a0Looking through the chart, you see that Dr. M. first noted the A Fib 4 years ago after the patient came in as walk-in the day after a syncopal episode. \u00a0Her ventricular rate then was 120. \u00a0Dr. M. started her on tenormin and lanoxin, which lowered her rate into the 50-60s. \u00a0Subsequently she infrequently complained of palpitations for which he prescribed her propranolol 10 mg prn. \u00a0The patient has no complaints. \u00a0She can walk the 4 blocks to the pharmacy without stopping. \u00a0There are about 15 EKGS in the chart, half of which show AFib, half of which are in NSR. \u00a0She also has HTN, for which she has been prescribed Lozol 2.5 mg and &#8220;AODM,&#8221; for which she takes Diabeta 5 mg. \u00a0 She also takes ASA 325 mg. \u00a0PMH is otherwise negative. \u00a0On exam, she is in Afib with an apical rate of 56, BP of 145\/85, clear lungs, 2\/6 holosystolic murmur, and trace pedal edema. Pedal pulses are full. \u00a0EKG shows Afib with ventricular rate 64, LVH by voltage criteria. \u00a0You order an echo which shows EF 58% with increased LV mass and concentric hypertrophy as well as moderate mitral regurgitation and LA diameter of 4.5 cm and estimated RVSP of 40.<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt; padding-left: 30px; font-size: 14px;\">&#8211; What further workup, if any, is warranted?<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt; padding-left: 30px; font-size: 14px;\">&#8211; Should she be anticoagulated? \u00a0If so, with what medication?<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0in 0in 10pt; padding-left: 30px; font-size: 14px;\">&#8211; What changes, if any, do you recommend for her cardiovascular medications?<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Management of Chronic Disease\/ Cardiology for the Internist \u00a0 Here are a few common clinical scenarios.\u00a0 Your job now is to say what you would do in these situations and why.\u00a0 In extreme detail.\u00a0 Detail the parts of your recommendation which stand on a firm evidence base and the parts which stand on shaky or&#8230;.<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":922,"menu_order":0,"comment_status":"open","ping_status":"open","template":"page-nosidebar.php","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"class_list":["post-921","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/jacobimed.org\/old\/wp-json\/wp\/v2\/pages\/921","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jacobimed.org\/old\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/jacobimed.org\/old\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/jacobimed.org\/old\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jacobimed.org\/old\/wp-json\/wp\/v2\/comments?post=921"}],"version-history":[{"count":5,"href":"https:\/\/jacobimed.org\/old\/wp-json\/wp\/v2\/pages\/921\/revisions"}],"predecessor-version":[{"id":3226,"href":"https:\/\/jacobimed.org\/old\/wp-json\/wp\/v2\/pages\/921\/revisions\/3226"}],"up":[{"embeddable":true,"href":"https:\/\/jacobimed.org\/old\/wp-json\/wp\/v2\/pages\/922"}],"wp:attachment":[{"href":"https:\/\/jacobimed.org\/old\/wp-json\/wp\/v2\/media?parent=921"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}