Questions About Identifying and Counseling Women at
Increased Risk for Breast Cancer

 

 

 

1. Which one
of the following patient characteristics is incorporated into the
NCI Risk Assessment tool?

 

a. Family history of breast
cancer in a sister

b. Age at diagnosis of mother
and/or sister affected by breast cancer

c. Family history of breast
cancer in a maternal aunt

d. Family history of breast
cancer in paternal relatives

e. Family history of ovarian
cancer

 

 

2. Which one
of the following percentages is correct regarding the absolute
breast cancer risk reduction after 5 years of tamoxifen administration in the
Breast Cancer Prevention Trial?

 

a. 1.3%

b. 1.7%

c. 2.6%

d. 25%

e. 50%

 

3. Which one
of the following regarding raloxifene is correct?

 

a. Is as effective as tamoxifen
in short-term breast cancer risk reduction

b. Acts as an estrogen
antagonist at the level of bone

c. Acts as an estrogen
antagonist at the level of the breasts

d. Is currently approved by the
Food and Drug Administration for breast cancer risk reduction

e. Is associated with an
increased risk of uterine cancer

 

4. Which one
of the following statements about breast cancer risk reduction options is correct?

a. Tamoxifen should not be given
as a chemopreventive agent to women older than 65.

b. Tamoxifen is the most
effective means of breast cancer risk reduction in women with known BRCA mutations.

c. Close surveillance is not an
appropriate option in women with BRCA mutations

d. Prophylactic mastectomy is
associated with a 90% reduction in the incidence of breast cancer.

e. Prophylactic oophorectomy is
an effective means of breast cancer risk reduction in only women with BRCA mutations.

 

 

Correct
answers:

1. a, 2
a, 3. c, 4. d