Malaria Prophylaxis

 

Falciparum Ovale Vivax Malarie
Age of RBCs infected All Young Young Old
Size of cell NL Big Big NL
% of Parasitemia >5% <5% <5% <5%
Liver stage no yes yes

no

Common prophylaxis drugs (eg, chloroquine, mefloquine and doxycycline) target blood stage of parasite (blood schizonticides).

Malaria with liver stage (Ovale, Vivax) should treated with tissue schizoticides (eg, atovaquone/proguanil).

 

If one person travel to chloroquine-resistant P falciparum (Sub-Saharan Africa, Southern & Southeast Asia),  prophylaxis with Atorvaquone-proguanil, Doxycycline, or Mefloquine (DOC for pregnancy)

If one person travel to chloroquine-susceptible P falciparum, prophylaxis with chloroquine, hydroxychloroquine 

If one person travel to area without P falcipraum area, prophylaxis with primaquine (screen G6-PD)

 

Further information for prophylaxis please check this Website